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Why is my nose itchy? I'm Dr. Manan Shah, I'm an ENT and allergist with Wyndly Health. When your nose is itchy, oftentimes, it's due to exposure to allergens. So what happens is, something you're allergic to gets into your nose, your body realizes it's not supposed to be there, or thinks it's not supposed to be there, and releases a molecule called histamine. Histamine is a molecule that's gonna cause your blood vessels to dilate, but it also makes you itchy, and so it's gonna wanna make you itc

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