Comet assay - Wikipedia
The single cell gel electrophoresis assay (SCGE, also known as comet assay) is an uncomplicated and sensitive technique for the detection of DNA damage at the level of the …
The comet assay: a method to measure DNA damage in individual …
Jun 27, 2006 · We present a procedure for the comet assay, a gel electrophoresis–based method that can be used to measure DNA damage in individual eukaryotic cells. It is versatile, …
Comet assay: a versatile but complex tool in genotoxicity testing
The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It can also be applied to cells isolated from treated animals. In this review, we highlight advantages …
The comet assay for DNA damage and repair: principles ... - PubMed
The comet assay (single-cell gel electrophoresis) is a simple method for measuring deoxyribonucleic acid (DNA) strand breaks in eukaryotic cells. Cells embedded in agarose on …
We describe here recent technical develop-ments, theoretical aspects, limitations as well as advantages of the assay, and modifications to measure cellular antioxi-dant status and …
Measuring DNA Damage Using the Alkaline Comet Assay in …
The comet assay is a widely used method that allows the measurement of both DNA damage and its repair in cells. For this, cells are treated with DNA-damaging agents and embedded into a …
The comet assay: past, present, and future - PMC - PubMed …
The alkaline comet assay (single cell gel electrophoresis) is the most widely used method for measuring DNA damage in eukaryotic cells (Neri et al., 2015). It detects strand breaks (SBs) …
The comet assay: past, present, and future - Frontiers
Aug 12, 2015 · Since the first report by Ostling and Johanson (1984) the comet assay has been widely used in genotoxicity testing of chemicals, in both in vitro and in vivo models. An …
Measuring DNA modifications with the comet assay: a …
Jan 27, 2023 · The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human.
The comet assay, also known as single-cell gel electrophoresis (SCGE), has become an attractive assay in the assessment of DNA damage. Its simplicity, sensitivity, speed and economy make …
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