The PyroGene™ Recombinant Factor C Assay is a quantitative, end-point assay for the detection of Gram-negative bacterial endotoxin. In this assay demonstration, we show how to perform an …

The meaning of PYROGEN is a fever-producing substance.

The PyroGene ™ Recombinant Factor C (rFC) Assay from Lonza is a quantitative assay that works through a single enzymatic step, uses no animal-derived products, and offers the same sensitivity as …

Pyrogens are fever-inducing substances that can be classified as exogenous or endogenous, with common exogenous pyrogens including bacterial components like lipopolysaccharide (LPS) and …

PyroGene is intended for use as an in vitro end-product endotoxin test for human and animal parenteral drugs, biological products, and medical devices. This product is not intended for use in the detection …

In the PyroGeneTM rFC Assay, activated Factor C directly cleaves a fluorogenic substrate, producing a signal that is read using a standard fluorescent plate reader.

The PyroGene Recombinant Factor C (rFC) Assay is an advanced, endotoxin-specific fluorescent assay (0.005 – 5.0 EU/ml range) for detecting Gram-negative bacterial endotoxin.

Read how to detect endotoxins in only 15 minutes using the fluorescent PyroGene™ assay and a CLARIOstar Plus microplate reader with EDR function here.

Endogenous pyrogens are proteins, such as interleukin-1, released by white blood cells in response to bacterial or viral infections.

The PyroGene® Test utilizes recombinant Factor C (rFC), an endotoxin-sensitive protein. rFC is used in combination with a fluorogenic substrate, an incubating fluorescence microplate reader and …