mRNA Technology: What It Is and How It Works - Pfizer
Pfizer’s next wave of mRNA scientific innovation is expanding in the infectious disease arena with vaccine development programs in flu (influenza) and shingles, as well as exploring respiratory combination vaccines. Pfizer is also exploring the versatility of this technology in the areas of rare genetic diseases.
Pfizer–BioNTech COVID-19 vaccine - Wikipedia
The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, [2][33] is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with the American company Pfizer to carry out clinical trials, logistics, and manufacturing. [46][47] It is authorized for use ...
FDA Approves and Authorizes Updated mRNA COVID-19 Vaccines …
The updated mRNA COVID-19 vaccines include Comirnaty and Spikevax, both of which are approved for individuals 12 years of age and older, and the Moderna COVID-19 Vaccine and Pfizer-BioNTech COVID ...
Pfizer and BioNTech Provide Update on mRNA-based …
Aug 16, 2024 · The combination candidate consists of Pfizer’s mRNA-based influenza vaccine candidate with the companies’ licensed COVID-19 vaccine. The Phase 3 trial measured two primary immunogenicity objectives (immunogenicity against SARS-CoV-2 as well as immunogenicity against influenza A and B), of which one was met.
Pfizer and BioNTech Announce Positive Topline Data for mRNA ...
Oct 26, 2023 · Lead formulations evaluated in the Phase 1/2 study demonstrated robust immune responses to influenza A, influenza B, and SARS-CoV-2 strains Safety profile of the mRNA-based combination vaccine candidates consistent with the companies’ COVID-19 vaccine The companies plan to start a pivotal Phase 3 trial in the coming months Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today ...
FDA Approves First COVID-19 Vaccine | FDA - U.S. Food and ...
FDA Office of Media Affairs. 301-796-4540. Consumer: 888-INFO-FDA. FDA approved the first COVID-19 vaccine, which has been known as the Pfizer-BioNTech COVID-19 Vaccine, and is now marketed as ...
Different types of COVID-19 vaccines: How they work
The mRNA in the vaccine doesn’t enter the nucleus of the cell, where DNA is kept. Both the Pfizer-BioNTech and the Moderna COVID-19 vaccines use mRNA. Vector vaccine. In this type of vaccine, material from the COVID-19 virus is placed in a modified version of a different virus
How the Pfizer-BioNTech Vaccine Works - The New York Times
Like the Moderna vaccine, the Pfizer-BioNTech vaccine is based on the virus’s genetic instructions for building the spike protein.. mRNA Inside an Oily Shell. The vaccine uses messenger RNA ...
Comparing the differences between COVID-19 vaccines
Sep 16, 2024 · Approval, authorization and safety. Pfizer-BioNTech COVID-19 vaccine 2024-2025 formula is authorized for people ages 6 months through 11 years. Comirnaty is approved for people age 12 and older. The vaccines that help protect against COVID-19 are safe and effective based on clinical trials and continued monitoring.
What’s Different About Messenger RNA (mRNA) Vaccines for ...
Messenger RNA (mRNA) vaccines, like the Pfizer and Moderna COVID-19 vaccines, teach cells how to make a protein that triggers an immune response if someone gets infected. When the vaccine is injected into the upper arm, the mRNA enters cells near the site of the injection and tells the cells to start making the same protein that is found in the ...