Chicago White Sox tagged Shota Imanaga early and often to win Game 1 of the Crosstown Classic over the Cubs 12-5. It's the Sox sixth win in seven games

Chase Meidroth, Colson Montgomery, Austin Slater and Mike Tauchman homered for the White Sox, who clobbered the Cubs 12-5 in the City Series on Friday.

Chase Meidroth, Colson Montgomery, Austin Slater and Mike Tauchman homered and Adrian Houser pitched effectively into the seventh inning as the host Chicago White Sox routed the Chicago Cubs 12-5 on Friday.

Since the White Sox won the last game on August 15, 2023, the Cubs have beat them eight straight games. There was one win in 2023, then the Cubs won all four in August of 2024. Earlier this season, the Cubs swept the White Sox, outscoring them 26-8.

This round of the City Series arrives as the July 31 trade deadline nears. The Cubs are in a position to buy while the White Sox will be looking to sell.

Recording a season-high 18 hits in a win over their crosstown rival Chicago Cubs, the White Sox lead MLB with 61 runs since the All-Star break.

The Cubs only recorded five hits against White Sox starter Adrian Houser, who held the Cubs scoreless through six innings, before surrendering a three-run blast to Reese McGuire in the seventh. Houser exited with two outs in the inning.

It's Friday, July 25 and the Cubs (60-42) are in Chicago to take on the White Sox (37-66). Shota Imanaga is slated to take the mound for Chicago against Adrian Houser for Chicago. The Cubs are 1-3 in the past four games and coming off a series loss to the Royals where they dropped two of three.

CHICAGO –– Center fielder Luis Robert Jr. is not in the White Sox starting lineup Friday against the Cubs.

The Sox have won six of seven since the All-Star break, none sweeter than Friday's 12-5 victory. The Cubs failed to pull even with Astros.

The Chicago Cubs (60-42) visit the South Side of Chicago to face the Chicago White Sox (37-66) Friday in the first game of a 3-game interleague series. First pitch from Rate Field is at 7:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

This article was originally published on www.si.com/mlb/whitesox as Chicago White Sox Provide Injury Update On Shane Smith. CHICAGO –– Shane Smith's rookie season hit a road bump just days after pitching in the 2025 MLB All-Star game.