Colton Cowser, James McCann and Anthony Santander led a home run parade to help the Orioles beat Detroit on Friday.

BOTTOM LINE: The Chicago White Sox, on a three-game losing streak, take on the San Diego Padres. San Diego is 43-36 in home games and 88-66 overall. The Padres have a 37-20 record in games when they ...

Manny Machado’s San Diego Padres play the Chicago White Sox on Sept. 21 at 8:40 PM ET, and will see starting pitcher Chris ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

A Petco Park clinch remains on the table for the Padres this weekend. Fernando Tatis Jr. made sure of it. Tatis smacked his second walk-off hit of the month -- a single to the right-center-field gap - ...

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.

Fernando Tatis Jr.'s walkoff double in the 10th inning helped the Friars open their final home (regular season) series of the year with a 3-2 win over the White Sox in front of yet another sellout ...

Fernando Tatis Jr. wins game with double leading off the 10th inning; Joe Musgrove throws six scoreless innings ...

The San Diego Padres will don the traditional pink City Connect jerseys tonight when they host the Chicago White Sox for the first of three games at Petco Park.

The Chicago White Sox (36-117) kick off a three-game series on Saturday against the San Diego Padres (87-66). The matchup ...