The translation of mRNA begins with the formation of a complex on the mRNA (Figure 4). First, three initiation factor proteins (known as IF1, IF2, and IF3) bind to the small subunit of the ribosome.

By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

The cap is later recognized by initiation factors, for translation. While transcription continues beyond the actual end of a gene, an endonuclease protein complex associated with the pre-mRNA ...

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

The concept of transcription and translation opposing each other to restrain tumor formation was so novel that Jana had to give this phenomenon a name: transcriptional-translational conflict. It thus ...

The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

Discover how they make in vitro transcription possible and refine reaction products to generate highly pure, homogeneous mRNA. Learn more about: The critical stages of mRNA synthesis ...

American Chemical Society. (2017, May 3). Imaging mRNA right where it is made: At the site of translation. ScienceDaily. Retrieved May 27, 2025 from www.sciencedaily.com / releases / 2017 / 05 ...