Production tips from Crystal Bio, TriLink Biotechnologies, Ginkgo Bioworks, Quantoom Biosciences, and Parexel.

The global mRNA synthesis and manufacturing market is projected to grow from USD 2,231.4 million in 2024 to USD 2,958.3 ...

We then showed that FOXG1 interacts with the mRNA of Grin1 and with two key ... by directly affecting both the transcription and translation of certain genes, FOXG1 may facilitate the hereditary ...

We then showed that FOXG1 interacts with the mRNA of Grin1 and with two key ... by directly affecting both the transcription and translation of certain genes, FOXG1 may facilitate the hereditary ...

This is known as gene regulation. This year, developmental biologist Victor Ambros and molecular biologist Gary Ruvkun are ...

Camp4 Therapeutics (CAMP) stock gains after J.P. Morgan and Piper Sandler launched its coverage with Overweight ...

Research into miRNAs may uncover new therapeutic strategies for conditions like cancer, cardiovascular disease, and ...

One study outlined the key areas that need to be overcome: the stability, immunogenicity, translation ... “Larger mRNA-based therapeutics are synthesised by in vitro transcription, which is ...

Embryogenesis entails dramatic shifts in mRNA translation and turnover that reprogram gene ... succeeding the major wave of zygotic mRNA transcription. Maternal and zygotic tRNA pools are distinct, ...

This valuable study reveals extensive binding of eukaryotic translation initiation factor 3 (eIF3) to the 3' untranslated regions (UTRs) of efficiently translated mRNAs in human pluripotent stem ...

IRE1α inhibitor STF improves glucose tolerance and insulin sensitivity in DIO mice. A. mRNA levels of ER stress genes in the eWAT from mice fed ND (normal diet) and HFD for 14 weeks, assessed by ...

"This approach yields pure RNA, free from length inconsistencies and impurities typically associated with transcription-based synthesis methods." Besides fully synthesizing mRNA chemically ...