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In the last decade, a series of studies highlighted the powerful potential of combining mRNA modification with lipid nanoparticle technologies, which led to the first approval of an LNP-mRNA vaccine.
The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...
Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered ...
Sanofi’s Pasteur vaccines unit and Translate Bio have expanded a collaboration to develop mRNA-based vaccines across all infectious disease areas. The deal builds on an agreement signed in 2018 ...