Three structures of the eukaryotic small ribosomal subunit in complex with initiator tRNA, mRNA and the initiation factors eIF1 and eIF1A have been solved; these structures offer insight into the ...

mRNA-specific translation. Protein synthesis-inducing cues increase global translational activity but initiate translation of only a subset of mRNAs. For example, netrin 1 and bdnf, ...

The researchers discovered that the RNAP transcribing the mRNA deploys two different anchors to rope in the ribosome and ensure a solid footing and start of protein synthesis.

Many ribosomes can be working on a single strand of mRNA at once. Protein synthesis isn't a slow process, either. A protein chain 400 amino acids long can be assembled in 20 seconds!

Precision therapy. Abe and his colleagues developed two designs. Among these, Cap-circRNA demonstrated superior performance, synthesizing up to 200 times more protein than commonly used circular ...

We found that the drive to conserve energy determines mRNA and protein number and location, affecting each molecular species differently depending on the length, lifetime and other properties of ...

New mRNA produces 200 times more protein: Hope for treatment of cancer and protein disorders. ScienceDaily . Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 02 / 250219111122.htm ...

During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together ...