As a key player in protein synthesis, mRNA technology is transforming therapeutics, offering solutions for cancer, genetic disorders, and regenerative medicine.

However, in the half-century since the structure of DNA was first elaborated, scientists have learned that RNA does much more than simply play a role in protein synthesis. For example, many types ...

This valuable study reveals extensive binding of eukaryotic translation initiation factor 3 (eIF3) to the 3' untranslated regions (UTRs) of efficiently translated mRNAs in human pluripotent stem ...

we observed significant discrepancies between the levels of Grin1 protein and the corresponding mRNA, proving that these discrepancies originated from a different rate of synthesis (and not ...

This evolutionary conservation highlights the fundamental role of tRNA in the essential process of protein synthesis. The basic structure and function of tRNAs have remained largely unchanged over ...

They discovered the existence of tiny RNA molecules, called microRNA (miRNA) that bind to mRNAs and prevent protein synthesis. Chemically, a miRNA is made of the same material that makes up mRNA.

These rRNAs are involved in mRNA binding and decoding ... which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery led to the concept of the ribosome ...