Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

The mRNA therapeutics field is rapidly evolving beyond vaccines to include treatments for cancer, genetic disorders and in vivo cell therapies, bringing with it diverse production challenges. As the ...

The success of the mRNA-based vaccines against SARS-CoV-2 merely hint at the healthcare implications of mRNA technology. More mRNA-based vaccines are in the works, as are mRNA-based therapeutics ...

The mRNA market is projected to reach $63.28 billion by 2025, indicating an all-time high global demand for mRNA vaccines and therapeutics. Now more than ever, robust process development and ...

Figure 2: Options in a typical mRNA synthesis workflow . Following mRNA synthesis, encapsulation (Figure 3) is a key step in the process to deliver mRNA into the target cells.

Development of hydrophobic tag purifying monophosphorylated RNA for chemical synthesis of capped mRNA and enzymatic synthesis of circular mRNA. Nucleic Acids Research , 2024; DOI: 10.1093/nar/gkae847 ...

Researchers at the University of Würzburg have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment ...

One of mRNA’s greatest advantages is the ability to rapidly iterate and optimize sequences, accelerating drug discovery and development. Advances in cell-free gene synthesis and in vitro transcription ...

Study reveals how cells regulate repair protein production to prevent DNA damage over-repair or under-repair, aiding cell ...

- Linea™ IVT Platform Delivers All The Benefits of Conventional IVT Without dsRNA Contamination - STONY BROOK, NY / ACCESSWIRE / July 29, 2024 /Applied DNA Sciences, Inc. (NASDAQ:APDN) (Applied ...

However, production of the mRNA used in vaccines is hindered by its production, which involves both chemical synthesis and a slower enzyme-mediated process.