Crispr has already secured a historic first approval for a CRISPR/Cas9 drug and has several more potential blockbuster ...
Nanoparticles have once again reached the spotlight, this time as a critical tool to combat the spread of covid-19. In this ...
The mRNAs are formulated in novel patented lipid nanoparticles, which prolong the half-life of the mRNA and deliver it to immunoactive antigen-presenting cells, which enhances T-cell responses.
CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.
Expert Rev Vaccines. 2012;11(1):55-67. A summary of the events taking place after intradermal injection of naked mRNA is given inFigure 1. Although formulation of mRNA vaccines and sophisticated ...
The Adrenaverse platform is a relatively new platform by Aquestive. This platform is essentially the 'secret-sauce' ...
This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...
Rosuvastatin with a 19-h half-life and atorvastatin with an 11–24-h half-life (parent drug and active metabolite) are particularly useful for this approach. Combination therapy with a statin ...
The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...
This useful study combines multiplexed RNA-FISH with downstream analyses and modelling to describe novel dendritic mRNA distribution and behavioural features. Although the downstream analysis pipeline ...
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