When someone is put on trial for a crime, it’s fair to expect that they’ll be alive, but that isn’t actually always the case: ...
Importance Quitting smoking is essential for stabilising and improving respiratory function in people with chronic obstructive pulmonary disease (COPD). Objective To evaluate the efficacy and safety ...
Asymptomatic severe aortic stenosis may lead to the progression to both symptoms and adverse outcomes if left untreated. The appropriate timing of intervention for these patients remains controversial ...
US Food and Drug Administration Approval Summary: Inavolisib With Palbociclib and Fulvestrant for Endocrine-Resistant, PIK3CA-Mutated, Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor ...
Objective: To address this gap, we conducted a pre-registered meta-analysis to synthesize findings from rigorously designed randomized controlled trials (i.e., low attrition, comparable baseline ...
Background: Autoimmune diseases, such as Crohn’s disease (CD) and systemic lupus erythematosus (SLE), lead to progressive multi-organ damage due to immune dysregulation and chronic inflammation.
A joint ASCO and Friends of Cancer Research task force invited industry and National Cancer Institute trial sponsors to contribute deidentified trial-level aggregate data on enrollment, major protocol ...
The win ratio is a method for analyzing a hierarchical composite outcome. It has been most widely used in randomized clinical trials (RCTs) in cardiovascular disease. We performed a review of ...
1 Department of Pharmacy, the First Affiliated Hospital of Army Medical University (Third Military Medical University), Chongqing, China 2 Pharmacy Department, Chongqing Emergency Medical Center, ...
Tirzepatide and semaglutide are highly effective medications for obesity management. The efficacy and safety of tirzepatide as compared with semaglutide in adults with obesity but without type 2 ...
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