The mutation, famously studied by the late Ben Barres and others, causes a certain protein to travel away from the nucleus down the axon in neurons. The team wondered if they could build a TRAM ...

The mutation, famously studied by the late Ben Barres and others, causes a certain protein to travel away from the nucleus ...

One argues that the effect of the mutation is on energy metabolism at the level of the axon. The other places the change at the level of the nucleus, with increased expression of the transcription ...