A protein was created where TDP-43 was fused to the SUMO2 protein and these fusion proteins were expressed in cells with or ...

Our lives are filled with binary decisions – choices between one of two alternatives. But what's really happening inside our ...

Moreover, previously recognized requirements for the accessory molecule CD14 in TLR4 endocytosis and endosomal signaling are likely attributable to CD14 binding as well as trafficking and transferring ...

Thirteen years ago, when Chris Farmer founded early-stage venture firm SignalFire with data analysis at the core of its investment strategy, many were skeptical about the approach — conventional ...

The firm's new LPs include giant pension plans, insurers, banks, and an Asian sovereign, Farmer said. Indeed, CalPERS, the largest pension fund in the U.S., has reportedly committed $100 million to ...

CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing immunity. Blocking this pathway restores immune function and improves survival ...

James is a published author with four pop-history and science books to his name. He specializes in history, strange science, and anything out of the ordinary.

Are there additional components/adaptors that contribute to lens development? Understanding the complexities of a pathway as critical as FGF signaling is necessary for future strategies to treating ...

Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. (Y.X., X.-Y.W., Z.-Y.H., H.Z., Z.-Y.Y ...

Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei 230601, China Clinical Research Unit, Changhai Hospital, Naval Medical University, Shanghai 200433, China ...