New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...

Infectious diseases are illnesses caused by pathogenic microorganisms—including viruses, bacteria, fungi, and parasites—that invade a host, replicate, and ...

Serotonergic G-protein-coupled receptors (GPCRs), including the 5-HT2A receptor (5-HT2AR) and 5-HT2CR, are key regulators of cortical signaling pathways and promising targets for neurotherapeutic drug ...

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other ...

The novel biosensor technology used in this study can also be transferred to other so-called G protein-coupled receptors (GPCRs), which act as crucial “signal receivers” in our cells and are of major ...

Daridorexant is a dual orexin receptor antagonist being developed by Nxera for the treatment of adult patients with insomnia and is approved and marketed in Japan as QUVIVIQ®Phase 3 trial of ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...

InterAx Biotech Ltd ("InterAx") and Alveus Therapeutics Inc. ("Alveus") today announced a strategic research collaboration and licensing agreement to develop a differentiated small molecule candidate ...

Mutations in the GNAO1 gene can lead to severe neurological disorders, leading to treatment-resistant epilepsy, developmental delay and movement disorders in children. Zinc supplementation has emerged ...

Domain Therapeutics Rebrands as Kainova Therapeutics Advancing Its Clinical Pipeline of GPCR-Modulating Therapies -- Kainova Therapeutics rebrand reflects expanding capabilities powering next stage of ...