The endothelium, which forms the inner lining of all blood vessels, is a highly selective barrier for blood constituents. Formation of gaps between endothelial cells (ECs), for instance during ...

They thus hypothesize that the interaction between S1PR1 and Integrin α2 is fundamental for the activation of Rac1 and Cdc42 and consequently for the polymerisation of actin; a reduction in this ...

Vascular Biology Program, Boston Children’s Hospital, MA (J.E.I., C.P., R.H.B.). Department of Surgery, Harvard Medical School, Boston, MA (J.E.I., C.P., R.H.B ...

Multiple myeloma (MM) is an incurable malignancy of bone marrow plasma cells characterized by wide clinical and molecular heterogeneity. In this study we applied an integrative network biology ...