POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Ding, B. , Wu, Y. , Zhang, Y. and Li, Y. (2024) CXCL10 Induces Lytic Reactivation of EBV through EXTL 1. Advances in ...

WVE-007 (INHBE GalNAc-siRNA for obesity) is on track to initiate a clinical trial in 1Q 2025; new preclinical data for WVE-007 demonstrate ...

Judo Bio, a biotechnology company pioneering oligonucleotide medicines delivered to the kidney, today announced the presentation of preclinical data t ...

Also, we’re taking advantage of endogenous machinery that is present in every cell of the body. In theory, we could design a small interfering RNA (siRNA)—the active ingredient in an RNAi ...

The siRNA or isRNA duplexes were obtained via annealing of antisense ... D.V. Kuprash (Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia). KB-3-1-MDR1-GFP and K562-MDR1-GFP cell lines ...

The global arachnid trade is threatening the world's most famous spider species. And it's primarily driven by souvenir collectors. Climate change and sea ice loss leaves polar bears exposed to ...

“We are innovating not only in our biology discovery ... oligonucleotide-based antisense and siRNA therapeutics, binding to asialoglycoprotein receptors expressed on the surface of hepatocytes ...

Currently, the biological sciences are served by three independent units: the Department of Biology, the Department of Microbiology and Plant Biology, and the Oklahoma Biological Survey. Through the ...

A bachelor of science degree in biology provides students with the intellectual and technical skills to succeed in a multitude of careers (e.g., medicine, forensics, genetics, laboratory sciences, ...