We summarize the numerous publications to date demonstrating the robust efficacy of RNAi in animal models of human disease upon direct (local) as well as systemic administration. These proof-of ...

This was motivated by the surprisingly weak anti-tumour activity of A-443654 as a single agent in preclinical models 79. Two kinases were identified in this screen: casein kinase 1, γ3 (CSNK1G3 ...

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The original model that was trained on 5 datasets (MIX 5 in the paper) can be found here. The figure below shows an overview of the different MiDaS models; the bubble size scales with number of ...

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