The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

But iOS 26 and Apple’s other developer betas include the company’s own transcription frameworks – and a test suggests that they match Whisper’s accuracy while running at more than twice ...

We studied the consequences of EPB41L4A-AS1 perturbation in breast cancer cells and found that it acts both in cis, to enhance transcription of the proximal EPB41L4A gene and additional genes in its ...

Similarly, Ziemniak et al. have produced a range of fluorescent 5′-cap analogues that are compatible with both transcription and translation. (26) However, the resulting mRNA products only carry one ...

More information: An Il12 mRNA-LNP adjuvant enhances mRNA vaccine–induced CD8 T cell responses, Science Immunology (2025). DOI: 10.1126/sciimmunol.ads1328 ...

More information: Aseno Sakhrie et al, Nanoparticle-Based mRNA Vaccine Induces Protective Neutralizing Antibodies Against Infectious Bronchitis Virus in In-Vivo Infection, Vaccines (2025).

Moderna MRNA -1.38% was once a darling of the first Trump administration, which went to great lengths to help the company develop its Covid-19 vaccine that protected millions of people from the virus.

TriLink’s CleanCap technology produces optimal 5′ cap structures with over 95% efficiency, creating a co-transcriptional capping solution that dramatically improves mRNA yield and process time ...