Translocation: The ribosome moves one codon down the mRNA. The tRNA in the A site moves to the P site, the tRNA in the P site ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

In this GEN webinar we will discuss emerging purification and quantitation techniques that work for the new generation of mRNA therapeutics beyond COVID-19 vaccines.

In a development that could shape cancer treatment strategies, researchers have found evidence that COVID mRNA vaccines can enhance the effectiveness of cancer immunotherapy and significantly improve ...

The performance of skilled behaviors requires a balance between consistency and adaptability. Although the neural mechanisms that regulate this balance have been extensively studied at systems and ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

Protection of Genetic Material: The nuclear envelope shields the DNA from the mechanical and chemical stresses of the ...

Background Hereditary haemorrhagic telangiectasia (HHT) and juvenile polyposis syndrome (JPS) can be caused by SMAD4 pathogenic variants. SMAD4 is a common transcription factor of the BMP/TGFβ ...