The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

Lipid nanoparticle (LNP) mRNA vaccines emerged during the COVID-19 pandemic to form an almost miraculous protection against a virus, which killed millions around the world. Aided by expedited ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

A research team from The University of Osaka and the Institute of Science Tokyo has developed a class of mRNA medicines that ...

Researchers from UConn's College of Agriculture, Health and Natural Resources (CAHNR) and College of Liberal Arts and Sciences (CLAS) have demonstrated that a novel protein-based nanoparticle can ...

Using capillary gel electrophoresis, researchers from the National Institute of Health Sciences in Kanagawa, Japan studied the factors that optimize chain-length distribution analysis of messenger RNA ...

Deadenylases shorten mRNA poly(A) tails and thereby regulate mRNA translation and decay. Recent studies have shown that these factors form different complexes. The recruitment of multifunctional ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered that m6A methylation regulates the production of proteins essential for ...

Researchers develop a self-regulating mRNA medicine that adjusts protein production based on disease-related signals.

TriLink’s CleanCap technology produces optimal 5′ cap structures with over 95% efficiency, creating a co-transcriptional capping solution that dramatically improves mRNA yield and process time ...