A research team has proposed a new live-attenuated influenza vaccine approach — generating proteolysis-targeting chimeric (PROTAC) influenza A virus as a live-attenuated vaccine by utilizing the ...

Live-attenuated vaccines are a very effective type of vaccine used in the prevention of diseases including influenza, chickenpox, measles, polio and TB.

Recently, a research team led by Prof. Si Longlong from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences has proposed a new live-attenuated influenza vaccine ...

The research data showed that the vaccine is attenuated and is not pathogenic in mouse models. ... live-attenuated influenza vaccines with broad protection against human and avian virus subtypes.

Beijing [China], July 4 (ANI): A research team led by Prof. SI Longlong from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences has proposed a new live ...

Immunizing children with intranasal live attenuated influenza vaccine (LAIV) does not appear to provide better protection against influenza than inactivated influenza vaccine (IIV), according to a ...

In the 2007-2008 flu season, the inactivated vaccine was more effective than the live attenuated vaccine in preventing laboratory-confirmed symptomatic influenza A (mostly H3N2) in healthy adults.

Level 2: Mid-level evidence The live attenuated flu vaccine (FluMist intranasally) appears more effective than the inactivated vaccine (Fluzone IM), based on a randomized trial of 8,352 ...

Live-attenuated influenza vaccine (LAIV) is not recommended for use in children aged 24 to 59 months with a history of recurrent wheezing or asthma, ...

But live attenuated influenza virus vaccines also have some drawbacks, he said. “These vaccines might be a challenge for pork producers to administer in a herd setting,” he said. “So we’re looking for ...

"This PROTAC vaccine technology could also be useful for generating live-attenuated vaccines against other types of pathogens," said Prof. SI. Reference: Si L, Shen Q, Li J, et al. Generation of a ...

Novel, needle-free, live-attenuated influenza vaccines with broad protection against human and avian virus subtypes. ScienceDaily . Retrieved June 11, 2025 from www.sciencedaily.com / releases ...