The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

Throughout an electric start to his NFL career, San Francisco 49ers quarterback Brock Purdy has seen caveats consistently ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

Winning your fantasy football matchups in Week 3 will mean making the right choices on these tough position calls.

Fantasy football analyst Sal Vetri delivers his keys to victory for Week 3 of the 2024 NFL season.

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

Injuries already are accruing across the NFL, knocking several star players out and forcing teams to turn to backups and ...

Pearsall (chest) ran routes on a side field Thursday, Matt Barrows of The Athletic reports.

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...