Los Angeles Rams coach Sean McVay is "not sad" he doesn't have to game plan for San Francisco 49ers stars Deebo Samuel and ...

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian McCaffrey and Deebo Samuel.

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Check out our Rams vs. 49ers how to watch guide to learn when they play and what free live streams are available ahead of ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

49ers GM John Lynch said Friday that Cowing "may get some [opportunities]" in Sunday's game against the Rams, Matt Barrows of The Athletic reports. With RB Christian McCaffrey (Achilles) on injured ...

The spread has moved one point in the Rams’ direction since Monday, likely because of the 49ers’ recent injury news ...

Pearsall (chest) ran routes on a side field Thursday, Matt Barrows of The Athletic reports.

The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers ...