The running back position got shaken up this offseason for the San Francisco 49ers. Christian McCaffrey and Isaac Guerendo are the only notable returning players in 2025. The rest of the depth chart is rounded out by rookie Jordan James and undrafted free agent Corey Kiner.

San Francisco 49ers general manager John Lynch revealed that star running back Christian McCaffrey was selected to address the team before their extended break leading up to training camp.

San Francisco 49ers All-Pro running back Christian McCaffrey shared an encouraging update on his health during team minicamp, saying that he feels "great" as he works his way back from being ravaged by injuries throughout the 2024 season.