A range of current precision oncology clinical trials are reliant on customized, targeted NGS-panel assays in order to ...

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Needham upgraded its price target for Bitdeer by 57 percent to $22 from $14, while giving it a “buy” rating, indicating an ...

These could be signs that you have an inherited intolerance to alcohol — and a mutated gene could be the culprit, according to Cleveland Clinic. This gene mutation hampers the body’s ability ...

HCC development in mice with MASH or whose hepatocytes expressed a cancer-inducing mutant protein called NRAS(G12V) (which also damages DNA and induces senescence) was accelerated when the mice ...

Amgen today announced that the U.S. Food and Drug Administration (FDA) has approved LUMAKRAS® (sotorasib) in combination with Vectibix® (panitumumab) for the treatment of adult patients with KRAS G12C ...

Gene Demby is a founding member of NPRs Code Switch team, where he serves as a host of the show's podcast. In 2020, Code Switch was named Apple's inaugural Podcast Of The Year. Demby's essays for ...

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...

Revolution Medicines Inc. has synthesized macrocyclic compounds acting as GTPase KRAS, NRAS, HRAS and their mutant inhibitors reported to be useful for the treatment of cancer. BioWorld Science Cancer ...

Similarly, the most common mutation in HRAS is the G12V substitution. As previously mentioned, NRAS has a mutation bias at codon 61, Q61R replacement at this position being the most frequent ...