Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

A new study reveals that while the molecular structure of liver metabolism remains intact during starvation, obesity disrupts ...

Researchers have discovered a type of "molecular glue" that can be used to inhibit certain pathological protein interactions.

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Such molecules would be suited to acting as quantum bits, or qubits, the basic unit of information in quantum systems. But ...

This structure has two helical chains each coiled round the same axis (see diagram). We have made the usual chemical assumptions, namely, that each chain consists of phosphate di-ester groups ...

A team at UCSF and Gladstone Institutes developed new drug candidates that show great promise against the virus that causes ...

Depending on who you follow on social media, you may have come across talk of a little-known herb called ashwagandha over the ...

As the clouds clear on computational crystal structure prediction, is the technique ready to empower mainstream materials ...

A new study from the Institute for Dynamics and Self-Organization suggests that tiny, one-sided interactions between ...

GenAI offers a realistic path forward in tackling previously undruggable targets, with the potential to reshape the entire ...

have tackled this problem head-on by designing a class of MOFs that incorporate structures called pillar[5]arene rings into a MOF framework (Fig. 1). Pillar[5]arenes are molecular rings that bind ...