To achieve this, the authors employed the technology of cellular reprogramming, which enables to convert cells ... first time a model for studying the neuronal pathology of Leigh syndrome caused ...

according to a new study carried out in a mouse model. Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms ...

To achieve this, the authors employed the technology of cellular reprogramming, which enables to convert cells ... first time a model for studying the neuronal pathology of Leigh syndrome caused ...

Mitochondria exist within cells and are responsible ... similar to those seen in patients with Leigh syndrome, Dr Richman says "So we've created a mouse model with the similar symptoms of ...

Without that enzyme, mitochondria fail to translate proteins efficiently leading to the symptoms recognized as Leigh syndrome. Studies in patient skin cells showed that the defects in translation ...

Leigh syndrome is a rare, progressive disease where mitochondria can't use the body's oxygen fast enough. Oxygen buildup in ...

The study was conducted with two different Leigh syndrome mouse models, as well as with fibroblast cells from patients. The results revealed that CBD acts at many levels within the cell ...

In the United States, the incidence of Leigh syndrome is about one in 40,000 live births. It's genetic and is caused by mutations in genes involved with cell metabolism. In some cases, there is a ...

The study was conducted with two different Leigh syndrome mouse models, as well as with fibroblast cells from patients. The results revealed that CBD acts at many levels within the cell ...

To achieve this, the authors employed the technology of cellular reprogramming, which enables to convert cells ... first time a model for studying the neuronal pathology of Leigh syndrome caused ...