Cell proliferation, differentiation and death are controlled by a multitude of cell?cell signals, and loss of this control has devastating consequences. Prominent among these regulatory signals is ...

In myasthenia gravis, complement plays a big role in what happens to the muscle end of the neuromuscular junction, explains ...

The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...

A UCSF analysis has found that the newer generation of much more effective diabetes medications are reaching only a fraction ...

Iptacopan targets one of the major proteins involved in the enzymes of the alternative pathway of complement, explains Carla ...

The American Society of Clinical Oncology (ASCO) first published a technology assessment for the use of chemoprevention agents for breast cancer risk reduction in 1999. 1 ASCO guidelines are updated ...

Many cancers involve upregulation of Aurora kinase B, which helps deregulate normal cell cycling to drive tumor proliferation. The kinase should therefore be a good therapeutic target, yet no ...