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Three-dimensional crystal structures of TTR in complex with several TTR amyloid inhibitors have been determined to drive the structure-based design of novel TTR fibril formation inhibitors with ...

and chemical intuition must be applied to design an initial search space and monitor its success. Human intuition and input will continue to be vital to the success of improving catalytic yields.

In this paper, we present a novel Discrete Variable Stiffness Actuator (DVSA) to be used in a compliant robotic manipulator for safe physical Human-Robot Interaction (pHRI). The novelty of this ...

while others “seem” to be human as a byproduct of their design, such as Claude or ChatGPT. The point is that responsible design requires developers to think more deeply about why such features ...

To date, advances in the field have largely benefited protein design, helping scientists create entirely new enzymes and antibodies faster than ever before. However, many human diseases stem from ...