The molecular structure of chikungunya may provide more guidance — and a way to stop it. The virus relies on two glycoproteins, E1 and E2, to enter and infect a cell. It targets cells found in ...

The chikungunya E2 covers much of its E1 partner on the virus surface, with the hydrophobic fusion loop of E1 clamped in the groove between domains A and B of E2 (Fig. 1). The Sindbis virus E2/E1 ...

Sri Laka is currently experiencing a large Chikungunya outbreak after 16 years and the current virus was of the Indian Ocean ...

Chikungunya virus (CHIKV ... Enlarged image on the right shows the orientation of the E2 and E1 envelope glycoproteins in the virion spikes. CP: Capsid protein. Reproduced with permission from ...

Panel A shows the organization of the chikungunya virus genome, including its nonstructural proteins 1 through 4 (nsP1–nsP4) and structural proteins C (capsid), E1–E3 (envelope glycoproteins ...

Sri Lanka is currently grappling with a major outbreak of the Chikungunya viral disease, marking the most significant resurgence of the virus in the country in nearly 20 years, according to renowned ...

India is one of the worst affected countries. The chikungunya virus has two surface proteins — E1 and E2. While E1 is a fusion protein, E2 very likely plays a role in binding the virus with ...