Researchers have established a method to create a network of perfusable blood vessels in organs-on-chips, enabling better ...

Miniature organs on a chip could allow us to do scientific studies with great precision, without having to resort to animal testing. The main problem, however, is that artificial tissue needs blood ...

In biomedical research, so-called organs-on-a-chip, also referred to as microphysiological systems, are becoming increasingly ...

Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity ...

Sickle cell disease (SCD) is a series of genetic blood abnormalities. Due to hemoglobin damage, your red blood cells (RBCs) lose their adaptable donut shape and adopt a "C" shape. These cells become ...

In this work, we investigated how targeted and nontargeted drug carriers affect the function of leukocytes in blood flow. We explored three primary mechanisms: (1) collisions in blood flow disrupt ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

A new, easily adopted, 3D-printed device will enable scientists to create models of human tissue with even greater control ...

Model more closely replicates natural environment of the pancreas, which will be essential for studying diabetes and ...

Regenerative Medicine and Stem Cell Laboratory ... (45°) for various 3D printed devices (Figure S4), sharkskin surface roughness on 3D printed PETg (Figure S5), cross sections of 3D printed ...

A decline in skin quality, its ability to heal, and its normal aging process is often observed in individuals with chronic hyperglycemia. A team of researchers from Inserm, the University ...

These disease models can be used to understand mechanisms ... of hiPSC-SMCs for regenerative wound healing in patients. 93 2023 3D-printed biomimetic flexible blood vessels with iPS cell–laden ...