The San Francisco 49ers are preparing for their Week 18 contest against the Arizona Cardinals on Sunday at State Farm Stadium in Glendale, Arizona. Both ...

The NFC West was turned upside down this season, as the San Francisco 49ers have been eliminated from the playoffs just one season removed from a trip to the Su ...

The San Francisco 49ers released its final injury report of the regular season. The following players were officially ruled ...

The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

The 49ers have ruled out two key starters versus the Cardinals in the regular season finale. Deebo Samuel and Deommodore ...

The 49ers entered the season as the NFC West betting favorites, and mid-season it seemed like the Cardinals were primed to contend for the crown, but as we get ...

Former Pittsburgh Steelers quarterback Josh Dobbs will start for the San Francisco 49ers in their game against the Arizona ...

Tua Tagovailoa is "very unlikely" to play in the Miami Dolphins' regular-season finale due to the hip injury that also kept him out last week against ...

Arizona State RB Cam Skattebo adds fuel to discussions linking him to San Francisco 49ers draft strategy amid backfield challenges.

Gibbs has taken the workhorse role in the first two games without Montgomery and run with the opportunity. He has back-to-back games with 100-plus rushing yards, and has continued to be a receiving ...

While some teams still try to make the playoffs, several NFL franchises could change their fortunes with a loss in Week 18, ...

Coming off a Week 17 breakout performance, Pearsall should have a featured role in the San Francisco offense Sunday with fellow wide receiver Deebo Samuel (ribs/wrist) ruled out. QB Brock Purdy (elbow ...