Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration.

At last, the stage was set for lifesaving blood transfusions. No more lambs’ or calves’ blood; no more transfusions from ...

Hypertonic saline refers to any saline solution with a concentration of sodium chloride (NaCl) higher than physiologic (0.9%). Commonly used preparations include 2%, 3%, 5%, 7%, and 23% NaCl.

Studies that compared hypotonic to isotonic maintenance solutions in children were selected. Case reports and studies in neonates or patients with a pre-existing history of hyponatraemia were excluded ...

Find out what's causing your cat is noisy breathing. Get insights into the potential causes and concerns, and learn how to ...

This study presents compelling evidence that the denitrosylase SCoR2 regulates cardioprotective metabolic reprogramming in the heart following ischemia/reperfusion injury. The findings are supported ...

Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, United States ...

Increased TGF-β1 promotes the phosphorylation and nuclear translocation of Smad2/3, sequentially activating the transcription ...

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