England have suffered significant injury news ahead of the Six Nations with Jamie George ruled out of their opening fixtures against Ireland and France.Hooker George, who has been replaced by Maro Itoje as captain,

England vice-captain Jamie George has been ruled out of the Six Nations opener against defending champions Ireland on February 1, the Rugby Football Union announced on Tuesday.

England have been struck by an injury crisis less than a fortnight before the Guinness Six Nations with vice-captain Jamie George heading a significant list of withdrawals from Steve Borthwick’s squad.

England lose Jamie George for Six Nations opener as injuries mount before Ireland clash - Alex Mitchell is also doubtful for Dublin trip, with Alex Coles, Jack van Poortvliet and Alex Dombrandt all ru

Jamie George’s miserable week was compounded when the hooker limped off with a hamstring problem late in Saracens’ Champions Cup defeat by Castres.

Ireland and England will meet at the Aviva Stadium in a blockbuster encounter on the opening weekend of the 2025 Six Nations Championship. The Irish are the two-time defending Six Nations

England have been hit by the loss of vice-captain Jamie George for their Guinness Six Nations opener against Ireland on February 1, with Alex Mitchell also a doubt for the Dublin showdown. Hooker George suffered a hamstring injury in Saracens’ Investec Champions Cup defeat by Saracens on Sunday and will miss the start of the tournament,

Flankers Tom and Ben Curry will start together for England for the first time against the defending champions in Dublin

Previous captain Jamie George has been ruled out of Englands first Six Nations; The England squad has been hit by five injuries including Georges after the weekends club matches and new players have been called up;

First-choice scrum-half Alex Mitchell, who missed the autumn Tests with a neck injury, could also miss the game with a knee problem he picked up against Munster on Friday

Simon Easterby’s team host old rivals England at the Aviva Stadium in their opening fixture of the 2025 championship

Scotland have added five players to their Six Nations squad ahead of their opening fixture against Italy at Murrayfield on Saturday, including Australia-born back row Alexander Masibaka after number eight Josh Bayliss dropped out with a groin injury.