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Researcher Resources

CIRM provides funding across all stages of research, from basic science to translational studies and clinical trials. This support drives best-in-class research aimed at developing innovative ...
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Unlocking the regenerative potential of hepatocyte plasticity for diseases of the biliary system

Research Objective The research will generate the know-how for replacing lost or injured bile ducts in the liver by reprogramming an abundant and related cell type that normally has a… ...
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Hedgehog Signaling in Cortical Development.

The Hedgehog (Hh) pathway plays a crucial role in embryonic development, acting both as a morphogenic signal that organizes tissue formation and a potent mitogenic signal driving cell proliferation.
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Alpha Clinics Network

The Alpha Clinics Network is funded and supported by the California Institute for Regenerative Medicine (CIRM). The Network features nine world-class medical centers throughout California with a ...
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CIRM invests $44 million to advance regenerative medicine research and manufacturing in California

South San Francisco, CA – The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, awarded $43.8 million to fund projects aimed at ...
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A maternal brain hormone that builds bone.

Muriel E Babey, William C Krause, Kun Chen, Candice B Herber, Zsofia Torok, Joni Nikkanen, Ruben Rodriguez, Xiao Zhang, Fernanda Castro-Navarro, Yuting Wang, Erika E Wheeler, Saul Villeda, J Kent ...
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Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing.

Chronic nonhealing wounds are debilitating and diminish one's quality of life, necessitating the development of improved strategies for effective treatment. Biomaterial- and cell-based therapies offer ...
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An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression.

Thanh Theresa Dinh, Menglan Xiang, Anusha Rajaraman, Yongzhi Wang, Nicole Salazar, Yu Zhu, Walter Roper, Siyeon Rhee, Kevin Brulois, Ed O'Hara, Helena Kiefel, Truc M ...
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Tissue-Engineered Three-Dimensional Platforms for Disease Modeling and Therapeutic Development.

Three-dimensional (3D) tissue-engineered models are under investigation to recapitulate tissue architecture and functionality, thereby overcoming limitations of traditional two-dimensional cultures ...
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Jingjing Li

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Year 3

CIRM SPARK funded UCR STRIDE (Summer Training and Research Inspiration for Diverse Pipeline Engagement toward Advancing Stem Cell Treatment) program has provided summer research experience and ...
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Magdalena Zernicka-Goetz

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