Leucine-rich repeat–containing protein 15 (LRRC15) is a cell surface protein that has emerged as a significant biomarker in cancer biology. This protein is minimally expressed in normal healthy tissue ...

The coronavirus disease 2019 (COVID-19) pandemic underscored the need for the development of tools that can visualize immune system activity in the context of viral inflammation. Although [18F]FDG PET ...

Fibroblast activation protein (FAP), a membrane-anchored peptidase, is highly expressed in cancer-associated fibroblasts in more than 90% of epithelial tumors and contributes to progression and worse ...

5B1 is a fully human, monoclonal antibody that has shown promise for the PET imaging of cancers expressing carbohydrate antigen 19.9 (CA19.9)—a carbohydrate prevalent in cells with aberrant ...

Recently introduced PET systems using silicon photomultipliers with digital readout (dPET) have an improved timing and spatial resolution, aiming at a better image quality than conventional PET (cPET) ...

PET imaging has the ability to offer valuable functional information, playing a key role in the diagnosis, staging, and evaluation of cancer; the planning of radiotherapy; and the diagnosis of some ...

TO THE EDITOR: In the published VISION trial results on 177Lu-vipivotide tetraxetan (Pluvicto; Novartis) use in metastatic castration-resistant prostate cancer, the mass and molar activity of prostate ...

PET is a powerful molecular imaging technique that can provide functional information on living objects. However, the spatial resolution of PET imaging has been limited to around 1 mm, which makes it ...

Prospective Histopathologic Comparison Between [18 F]PSMA-1007 PET/CT and [18 F]Fluciclovine PET/CT of Intraprostatic Tumor Detection: The TRACER Study ...

Time-of-flight (TOF) PET uses very fast detectors to improve localization of events along coincidence lines-of-response. This information is then utilized to improve the tomographic reconstruction.

The development of noninvasive imaging techniques using monoclonal antibodies (mAbs) is a quickly evolving field. Immuno-PET uses positron-emitting isotopes to track the localization of mAbs with ...

TO THE EDITOR: We refer to the recent Invited Perspective which proposes that there is now a reduced role for V/Q scintigraphy in the detection of pulmonary embolism (PE) given the emergence of CT ...