The translation of mRNA begins with the formation of a complex on the mRNA (Figure 4). First, three initiation factor proteins (known as IF1, IF2, and IF3) bind to the small subunit of the ribosome.

In prokaryotic cells, transcription (DNA to mRNA) and translation (mRNA to protein) are so closely linked that translation usually begins before transcription is complete.

The mRNA that is created in the process of transcription comprises a sequence of nucleotides. A set of three-letter combinations of nucleotides is called a codon.Codons can either encode a specific ...

Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in ...

The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

Also, the mRNA retention caused by SARS-CoV-2 was similar to the retention affected by ORF6 alone, which inhibited the export of mRNA species that caused transcription and immune regulation.

A research team from The University of Osaka and the Institute of Science Tokyo has developed a class of mRNA medicines that ...

The concept of transcription and translation opposing each other to restrain tumor formation was so novel that Jana had to give this phenomenon a name: transcriptional-translational conflict. It thus ...

Transcription is the first step in the synthesis of proteins from specific gene sequences. In this process, the genetic information in the DNA is copied to an mRNA with the help of an enzyme ...

Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs).