Wednesday night's showdown between the Oklahoma City Thunder and Cleveland Cavaliers is chock full of enough fascinating matchups and overall basketball excellence to mark this as one of the season's can't-miss games.

Predictions, picks and odds as the OKC Thunder faces the Cleveland Cavaliers on the road Wednesday. Plus, injury updates and news.

The Thunder (30-5) have won a franchise-best 15 in a row. The historic win streak has catapulted them to the top of the standings with a massive first-seed cushion. They collected a statement win over the Boston Celtics on Sunday. Shai Gilgeous-Alexander had 33 points, 11 rebounds and six assists.