[2] Patients with diffuse cutaneous scleroderma with skin thickening on the proximal extremities or the trunk are in highest danger of developing SRC, at 20% to 25%, and so should be followed ...

Scleroderma is an autoimmune condition that primarily causes thickening of your skin. For some people, bladder or urinary problems may also develop. Some treatments for scleroderma may also cause ...

Considering findings of naturally acquired ... is constitutively overexpressed by fibroblasts present in skin fibrotic lesions, including scleroderma. The overexpression of connective tissue ...

Scleroderma affects approximately 300,000 people in the U.S., with about one-third developing systemic disease, which can affect major organs such as the lungs, kidneys or heart. Women are four ...

Scleroderma is a rare, autoimmune connective tissue and rheumatic disease that primarily causes inflammation in the skin, and can lead to inflammation in other parts of the body, according to the ...

Of note, SSc has traditionally sometimes also been called scleroderma, but strictly speaking, this term refers only to skin ...

Scleroderma is a rare disease in which a person's immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, ...

Episodes of Raynaud's phenomenon, a common feature of systemic sclerosis (SSc, also known as scleroderma), were ... and the ...