In five years since AlphaFold's debut, it has transformed basic biochemical research. But its long-term effect on drug ...

Select an option below to continue reading this premium story. Already a Honolulu Star-Advertiser subscriber? Log in now to continue reading. Moreover, protein folding doesn’t happen in isolation.

Protein folding is a critical process by which linear chains of amino acids adopt specific three‐dimensional conformations essential for biological function. In recent years, studies have increasingly ...

Researchers from Northwestern University and the Institute for Industrial Science at the University of Tokyo say they have developed a new high-throughput approach known as cDNA display proteolysis to ...

Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into ...

A landmark study by researchers at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University reveals how a tiny cellular machine called TRiC directs the folding of ...

Misfold an origami swan and the worst that happens is you wind up with an ugly paper duckling. Misfold one of the vital proteins in your body – each of which must be folded in a particular way to ...

Scientists have been studying how proteins fold for decades. This research got a boost in late 2020, when AlphaFold proved it could predict protein structures with great accuracy. But what exactly ...

Repeat proteins, defined by sequential arrays of short structural motifs, offer an intriguing departure from the folding behaviour of conventional globular proteins. Their modular architecture enables ...

Much of our understanding of proteins in general is relative to their function in the human diet. To be sure, one of the major functions of protein in the human body is to provide the structural ...