These findings suggest that clone size at PNH onset may serve as a prognostic factor for disease burden and MAVEs/TEs, aiding in clinical decision-making about treatment initiation or maintenance.

A PNH diagnosis meant Bob's bone marrow was not producing healthy blood cells. "Those defective red blood cells in my body were wreaking havoc," he said. Throughout the entire treatment process ...

PNH is a rare, life-threatening disease of the blood characterised by destruction of red blood cells, blood clots and impaired bone marrow function, causing fatigue, recurrent infections and ...

This first-in-class, oral Factor D inhibitor can now be used as an add-on to ravulizumab or eculizumab for treating paroxysmal nocturnal haemoglobinuria (PNH) in adults with residual haemolytic ...

Along with haemolysis, people with PNH can suffer life-threatening blood clots and impaired bone marrow function. The median survival after diagnosis is 10 years, although some patients can ...