Cutting-edge experiments show that the hormone leptin, which is secreted by fat cells, promotes fat loss by activating the release of catecholamine signalling molecules from neurons wrapped around the ...

Lipolysis in fat tissue plays an important role in the development of metabolic disturbances, a characteristic feature of chronic kidney disease (CKD). In the present study, we tested the hypothesis ...

The inefficient breakdown of fats predicts later weight gain and metabolic complications such as type 2 diabetes in women, researchers report. Low levels of hormone-stimulated lipolysis -- a ...

Cachexia affects the majority of patients with advanced cancer and is associated with a reduction in treatment tolerance, response to therapy, quality of life, and duration of survival. It is a ...

In this review, I focus on recent studies using magnetic resonance spectroscopy (MRS) that have implicated ectopic lipid accumulation in the pathogenesis of insulin resistance in muscle and the liver ...