If these enzymes are not present or functional then the reactions will not occur, so the breakdown of glucose is controlled ... greater quantity of ATP. A pyruvate molecule enters the mitochondria ...

The researchers identified the structure ... pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport pyruvate, a molecule ...

Aerobic metabolism converts one glucose molecule into 30-32 ATP molecules ... identify ALDH4A1 as a component of the mitochondrial pyruvate carrier complex, which plays a non-canonical role ...