Please provide your email address to receive an email when new articles are posted on . The next generation of ophthalmic fluoroquinolones is finally a reality. With two new so-called “fourth ...

And all three of those qualities are present in three drugs.” Gatifloxacin is a fourth-generation, 8-methoxy-fluoroquinolone antibiotic approved by the FDA in 1999 for oral administration.

Second- and third-generation fluoroquinolones have been used in the past for prophylactic antibiotics but have limited degrees of gram-positive coverage. Newer fourth-generation fluoroquinolones ...

This study was designed to investigate the penetration of second-, third- and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.

Expert Rev Anti Infect Ther. 2010;8(11):1293-1305. Moxifloxacin is a broad spectrum, fourth-generation fluoroquinolone with activity against S. aureus (except for MRSA strains), Gram-negatives and ...