Precision gene editing can be achieved by base editing, nucleotide editing, or editing of small or large gene fragments. The specific mechanisms include various DNA repair pathways. Many precision ...

Genome editing is a powerful biotechnology tool that allows scientists to make precise changes to an organism's DNA. It involves the use of specialized enzymes, known as engineered nucleases or ...

New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime ...

A groundbreaking gene-editing method from UT Austin is changing the game for treating complex genetic diseases like cystic ...

Gene editing is now reaching the mainstream, ushering in a new era of genetic manipulation. Traditionally, inserting or deleting entire genes, regulating their expression, and altering specific ...

The energy factories in our cells contain their own genes, and genetic mutations in them can cause deadly inherited diseases. These oblong-shaped organelles, or mitochondria, translate genes into ...

Manipulating “thresholds” with mitochondrial gene editing tools. By focusing on the genetic roots of neurodegenerative diseases, mitochondrial DNA editing represents a shift in therapeutic strategies.

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...