Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat ...

The field of cancer research has increasingly focused on the intricate interplay between regulated cell death (RCD) pathways and the immune microenvironment in tumor progression and treatment.

Researchers at the University of Kansas have discovered a human gene, the protein PARP14, plays a role in regulating ...

Donor-Specific B Cells in Transplantation. The major goal of this project is to determine the properties of donor-specific B cells in recipients that maintain stable graft function and in those that ...

Trained immunity is reshaping our understanding of host defense by demonstrating that innate immune cells once thought to lack memory can be reprogrammed to mount heightened responses to subsequent ...

Long cell-free DNA fragments predict early-progression in patients with advanced or metastatic cancer treated with immune-checkpoint inhibition. Measure of minimal residual burden on circulating tumor ...

Myeloid cells constitute essential components within the immunosuppressive microenvironment of various tumors, significantly influencing cancer progression and resistance to therapeutic interventions.