Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities. The ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...

In a milestone achievement, a whole chromosome has been created from scratch by scientists for the first time ever. The tRNA Neochromosome is a man-made chromosome of the common baker's yeast ...

A new study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences has reveals that the contribution of cells expressing maternal or paternal X ...

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, ...

A Brazilian woman’s routine post-miscarriage tests led to a rare genetic revelation that surprised doctors and adds to our ...