Scleroderma is a chronic autoimmune disease of women. Over time, people living with scleroderma develop progressive and irreversible scarring. Scarring, called fibrosis, affects the lungs, heart and ...

Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood. However, the defining characteristic of ...

Over the years, the molecule nicotinamide adenine dinucleotide (NAD+) has gone from being a player in some biochemical pathways to a crucial substrate required by proteins that help control longevity ...

UCLA researchers have discovered a previously unrecognized type of progenitor cell that, though rare in most regions of the human prostate, is found in uncommonly high numbers in inflamed areas of the ...

Click to share on X (Opens in new window) X Click to share on Facebook (Opens in new window) Facebook Design by Evelyn Mousigian. Dr. John Varga, rheumatology, internal medicine and dermatology ...

NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous ...

Researchers at Cerevance Inc. and Cerevance Ltd. have identified heterobicyclic amides acting as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) inhibitors reported to be useful for the ...

Aeovian Pharmaceuticals Inc. has prepared tricyclic fused imidazole compounds acting as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) inhibitors reported to be useful for the treatment of ...

Longevity research always reminds me of the parable of blind men and an elephant. A group of blind men, who’ve never seen an elephant before, each touches a different part of the elephant’s body to ...